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Odontogenic Graft Obtained From Human Tooth and Low Level Laser Therapy
Sponsor: Istanbul Saglik Bilimleri University
Summary
This clinical trial aims to evaluate the effectiveness of an odontogenic graft obtained from extracted human teeth, with and without adjunctive low-level laser therapy (LLLT), on bone regeneration following posterior tooth extraction in systemically healthy adult patients. The study investigates whether the combination of autogenous tooth-derived graft material and LLLT enhances alveolar bone healing and preservation compared to grafting alone, prior to implant-supported posterior rehabilitation.
Official title: Use of Odontogenic Graft Obtained From Human Tooth and Low Level Laser Therapy
Key Details
Gender
All
Age Range
18 Years - 65 Years
Study Type
INTERVENTIONAL
Enrollment
21
Start Date
2026-02-02
Completion Date
2026-09-01
Last Updated
2026-05-29
Healthy Volunteers
Yes
Conditions
Interventions
Autogenous Tooth-Derived Bone Graft
Autogenous Tooth-Derived Bone Graft prepared using the BonMaker® ATB device from extracted human teeth. Following atraumatic tooth extraction, teeth will be mechanically ground and chemically processed according to the manufacturer's standardized protocol to obtain particulate autogenous graft material containing dentin and enamel components. The graft material will be placed immediately into extraction sockets for alveolar ridge preservation prior to implant placement.
Low-Level Laser Therapy (LLLT)
Adjunctive low-level laser therapy (LLLT) performed using a 650 nm diode laser device (Woodpecker DTE D-Laser Blue) with a 6 mm fiber applicator in continuous contact mode at an output power of 25 mW and an energy density of 0.500 J/cm². Laser irradiation will be applied to grafted extraction sockets immediately after extraction, after flap closure, and during postoperative follow-up visits according to a standardized treatment protocol to enhance soft tissue healing and bone regeneration.
Locations (1)
Health Sciences University
Istanbul, Uskudar, Turkey (Türkiye)