Clinical Research Directory

Inclusion Criteria: * Men and women between 18 and 75 years of age. * Normal-weight volunteers (BMI of 18.5-24.9 kg/m²). * Subjects must be able to understand and willing to sign the informed consent form, and must comply with all study procedures and requirements. Exclusion Criteria: * Presence of chronic gastrointestinal pathology. * Lactating or pregnant women, or those planning to become pregnant. * Individuals who have taken antibiotics within the 3 months prior to the study. * Individuals currently taking supplements (plant-derived, fiber, or probiotics) unless they are willing to discontinue use during the 4-day study intervention and ensure a minimum washout period of 14 days prior to baseline measurements. * Individuals with an alcohol intake \> 80 g/day. * Presence of allergy or intolerance to artichoke. * Individuals undergoing treatment with anticoagulants, immunosuppressants, or cytotoxic agents. * Presence of renal or hepatic failure. * Presence of immunodeficiency or being HIV positive. * Subjects with any type of cancer, those undergoing cancer treatment, or those for whom at least 5 years have not passed since remission. * Presence of weight loss greater than 5% in the 6 months prior to the trial. * Lack of time or geographical availability to attend the study visits. * Failure to sign the informed consent form. * Difficulty in undergoing blood extraction/collection. * Having donated blood within 14 days prior to the baseline visit. * Individuals who demonstrate difficulty swallowing capsules, tablets, pills, or similar.