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Summary
In the UK, babies born at 22 weeks of pregnancy have only been offered survival-focused care (sometimes called resuscitation or stabilisation) since 2019. Very few babies are born this early each year and sadly a lot of them do not survive. Therefore, healthcare teams don't have much information about this new population of tiny babies and there is much to learn about how they respond, the problems they face and the best way for intensive care units to look after them. This study aims to collect information available in babies' medical notes, analyse it and share learning to start improving this knowledge. There will be no changes to the babies' care, only observation of what happens. A small team of doctors and nurse practitioners who have/are looking after a baby, will put a small amount of selected information, without 'identifiers' such as the baby's name, date of birth or hospital number, onto a secure database platform at Imperial College London (a university). Researchers will analyse the information from all the babies around the UK together to look for trends and to describe common things that happen to them, as well as their outcomes. Parents will be made aware this information is being collected and used through a leaflet. It will not be possible to identify an individual baby in the results. The investigators are aiming for around 45 hospitals across the UK to participate. Babies born at 22 weeks gestation, who are attended to at birth by a neonatal team (or admitted) at an intensive care site over a 12-month period will be included. While collecting this information will not impact the babies included, it may help the treatment of babies born early in the future and give families more accurate information about what they might expect to happen.
Official title: Clinical Management and Short-Term Outcomes of Neonates Born at 22 Weeks in the UK (The 22 Week Study)
Key Details
Gender
All
Age Range
Any - Any
Study Type
OBSERVATIONAL
Enrollment
100
Start Date
2025-06-01
Completion Date
2027-12
Last Updated
2026-06-24
Healthy Volunteers
No
Conditions
Interventions
Not applicable (observational study)
Not applicable (observational study)
Locations (50)
Neonatal Unit, James Cook University Hospital
Middlesbrough, Teeside, United Kingdom
Neonatal Unit, University Hospital of Wales
Cardiff, Wales, United Kingdom
Neonatal Unit, Singleton Hospital
Swansea, Wales, United Kingdom
Neonatal Unit, Aberdeen Maternity Hospital
Aberdeen, United Kingdom
Neonatal Unit, William Harvey Hospital
Ashford, United Kingdom
Neonatal Unit, Royal Jubilee Maternity Hospital
Belfast, United Kingdom
Neonatal Unit, Birmingham Heartlands Hospital (University Hospitals Birmingham)
Birmingham, United Kingdom
Neonatal Unit, Birmingham Women's and Children's Hospital
Birmingham, United Kingdom
Neonatal Unit, Royal Bolton Hospital
Bolton, United Kingdom
Neonatal Unit, Bradford Royal Infirmary
Bradford, United Kingdom
Neonatal Unit, Southmead Hospital
Bristol, United Kingdom
Neonatal Unit, St Michael's Hospital
Bristol, United Kingdom
Neonatal Unit, Lancashire Women & Newborn Centre
Burnley, United Kingdom
Neonatal Unit, Rosie Maternity Hospital
Cambridge, United Kingdom
Neonatal Unit, Ashford & St Peter's Hospital
Chertsey, United Kingdom
Neonatal Unit, Ninewells Hospital
Dundee, United Kingdom
Neonatal Unit, Simpson Centre for Reproductive Health
Edinburgh, United Kingdom
Neonatal Unit, Medway Maritime Hospital
Gillingham, United Kingdom
Neonatal Unit, Princess Royal Maternity Hospital
Glasgow, United Kingdom
Royal Hospital for Children, Queen Elizabeth University Hospital
Glasgow, United Kingdom
Neonatal Unit, Hull Royal Infirmary
Hull, United Kingdom
Leeds Neonatal Service
Leeds, United Kingdom
Neonatal Unit, Leicester Royal Infirmary
Leicester, United Kingdom
Neonatal Surgical Unit, Alder Hey Children's Hospital
Liverpool, United Kingdom
Neonatal Unit, Liverpool Women's Hospital
Liverpool, United Kingdom
Imperial College
London, United Kingdom
Neonatal Surgical Unit, Great Ormond Street Hospital
London, United Kingdom
Neonatal Unit, Chelsea and Westminster Hospital
London, United Kingdom
Neonatal Unit, Homerton University Hospital
London, United Kingdom
Neonatal Unit, King's College Hospital
London, United Kingdom
Neonatal Unit, Queen Charlotte's and Chelsea Hospital
London, United Kingdom
Neonatal Unit, Royal London Hospital
London, United Kingdom
Neonatal Unit, St George's Hospital
London, United Kingdom
University College Hospital
London, United Kingdom
Neonatal Unit, Luton & Dunstable Hospital
Luton, United Kingdom
Neonatal Unit, St Mary's Hospital
Manchester, United Kingdom
Neonatal Unit, Royal Victoria Infirmary
Newcastle upon Tyne, United Kingdom
Neonatal Unit, Norfolk & Norwich University Hospitals
Norwich, United Kingdom
Neonatal Unit, Queen's Medical Centre, University Hospital Nottingham
Nottingham, United Kingdom
Neonatal Unit, Royal Oldham Hospital
Oldham, United Kingdom
Neonatal Unit, John Radcliffe Hospital
Oxford, United Kingdom
Neonatal Unit, Derriford Hospital
Plymouth, United Kingdom
Neonatal Unit, Queen Alexandra Hospital
Portsmouth, United Kingdom
Neonatal Unit, Royal Preston Hospital
Preston, United Kingdom
The Jessop Wing
Sheffield, United Kingdom
Neonatal Unit, Princess Anne Hospital
Southampton, United Kingdom
Neonatal Unit, University Hospital of North Midlands
Stoke-on-Trent, United Kingdom
Neonatal Unit, Arrowe Park Hospital
Upton, United Kingdom
Neonatal Unit, University Hospital Wishaw
Wishaw, United Kingdom
Neonatal Unit, New Cross Hospital
Wolverhampton, United Kingdom