Clinical Research Directory
Browse clinical research sites, groups, and studies.
Letrozole vs. Clomiphene Citrate Plus Tamoxifen for Ovulation Induction and Pregnancy Outcomes.
Sponsor: Sana'a University
Summary
Infertility is a common reproductive health problem. Ovulation induction is a key treatment for women with anovulatory infertility. Letrozole and clomiphene citrate are widely used medications for ovulation induction. Tamoxifen has also been used as an alternative or adjunct therapy. This randomized clinical trial aims to compare the effectiveness of letrozole versus clomiphene citrate combined with tamoxifen for ovulation induction and pregnancy outcomes in infertile women. The outcomes include ovulation rate, pregnancy rate, endometrial thickness, follicular development, Miscarriage rate, and Live birth rate. The study will be conducted at Al-Thawra Hospital in Sana'a, Yemen, under the supervision of Sana'a University. Keywords: Infertility, Ovulation Induction, Letrozole, Clomiphene Citrate, Tamoxifen
Official title: Letrozole Versus Clomiphene Citrate Plus Tamoxifen for Ovulation Induction and Pregnancy Outcomes in Infertile Women: A Randomized Clinical Trial
Key Details
Gender
FEMALE
Age Range
18 Years - 40 Years
Study Type
INTERVENTIONAL
Enrollment
240
Start Date
2023-05-01
Completion Date
2026-05-30
Last Updated
2026-06-01
Healthy Volunteers
No
Conditions
Interventions
Letrozole
Letrozole was administered for ovulation induction in infertile women according to the study protocol.
Clomiphene Citrate + Tamoxifen
Clomiphene citrate combined with tamoxifen was administered for ovulation induction in infertile women according to the study protocol.
Locations (1)
Al-Thawra Hospital
Sanaa, Sana'a, Yemen