Clinical Research Directory

Inclusion Criteria: Participants will be eligible for inclusion if they meet all of the following criteria: Female participants diagnosed with lower-limb lipedema. Age between 25 and 45 years old. * Clinical diagnosis of lipedema confirmed by the treating physician or specialist physiotherapist. * Lipedema stage II or stage III based on clinical presentation, including disproportionate fat deposition, pain/tenderness, easy bruising, tissue nodularity, or lobular tissue changes. * Scheduled for or recently underwent lower-limb liposuction for lipedema management. * Body mass index (BMI) between 25 and 35 kg/m². * Medically stable and cleared by the treating surgeon to start postoperative physiotherapy. * Ability to understand instructions and comply with treatment visits and assessment procedures. * Willingness to wear prescribed compression garments according to the postoperative protocol. 3.2 Exclusion Criteria * Primary or secondary lymphedema unrelated to lipedema, unless clearly differentiated and documented. * Lipedema stage IV with advanced lipo-lymphedema requiring complex decongestive therapy beyond the study protocol. * BMI greater than 35 kg/m² or less than 25 kg/m². * Uncontrolled diabetes mellitus, uncontrolled hypertension, severe cardiovascular disease, renal disease, hepatic disease, or active systemic inflammatory disease. * Deep vein thrombosis, active thrombophlebitis, severe peripheral arterial disease, or untreated varicose complications. * Active infection, open wounds, skin ulceration, cellulitis, or significant postoperative complications preventing mechanical therapy. * Known coagulopathy, current anticoagulation therapy not cleared by the surgeon, or high bleeding risk. * Pregnancy or lactation. * Previous lower-limb liposuction within the preceding 12 months. * Use of other structured edema-reduction interventions during the study period outside the assigned protocol. * Inability to attend scheduled follow-up assessments.