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NOT YET RECRUITING
NCT07619469

Motion Sickness Severity and Sensorimotor Performance

Sponsor: Istinye University

View on ClinicalTrials.gov

Summary

Background: Motion sickness (MS) is a common syndrome characterized by autonomic and behavioral symptoms, such as nausea and dizziness, resulting from exposure to motion stimuli. Its pathophysiology is closely linked to sensory conflict and postural instability theories. While previous studies suggest that postural control, proprioception, and reaction times are affected in individuals susceptible to MS, there is a lack of comprehensive, comparative research evaluating all these parameters concurrently within the same cohort using standardized methods. Objective: This study aims to systematically measure balance, proprioceptive sensitivity, coordination, and reaction time parameters, and quantitatively analyze their relationship with motion sickness severity. Methodology: In this prospective, cross-sectional study, at least 41 participants aged 18-40 with motion sickness will be recruited. Participants will undergo motion sickness susceptibility and severity grading using the Motion Sickness Susceptibility Questionnaire Short Form (MSSQ-SF) and the Graybiel Scale. Objective assessments will include static and dynamic balance testing (ProKin®), knee joint position sense (Clinometer app), manual dexterity and dynamic balance coordination (Nine-Hole Peg Test, Tandem Walk, Romberg Test), and upper/lower extremity reaction time measurements (BlazePod system).

Official title: The Relationship of Balance, Proprioception, Coordination, and Reaction Time Measurements With Motion Sickness Severity in Individuals With Motion Sickness: A Cross-Sectional Study

Key Details

Gender

All

Age Range

18 Years - 40 Years

Study Type

OBSERVATIONAL

Enrollment

41

Start Date

2026-06-01

Completion Date

2026-08-05

Last Updated

2026-06-02

Healthy Volunteers

No

Interventions

OTHER

Standardized Sensorimotor Assessment and Motion Sickness Provocation Protocol

Participants will undergo a standardized battery of sensorimotor assessments, including static/dynamic balance tracking, knee joint position sense testing, manual dexterity/coordination tasks, and upper/lower extremity reaction time measurements, alongside a controlled motion sickness provocation session using a randomized chair-rotation protocol."