Clinical Research Directory

Inclusion Criteria: * Adults (≥18 years) with symptomatic or asymptomatic, paroxysmal or persistent atrial fibrillation * First diagnosis of AF within the last 36 months * At least one documented episode of AF on ECG, Holter monitoring, or eligible Smart Watch Device * No prior catheter ablation for AF Exclusion Criteria: * Persistent AF \>3 years or longstanding persistent AF * Previous AF-Ablation * Ongoing continuous AAD therapy with Amiodarone at baseline * History of failed continuous AAD therapy with \> 1 agent. Exceptions are Beta blocker, Verapamil or "pill in the pocket"-therapy * Left Atrial Volume Index (LAVI) \> 50mL/m2 * Severe mitral regurgitation * Contraindications to anticoagulation therapy * Severe pulmonary or renal disease * Pregnancy, active cancer disease * Any condition or disease which is contraindication for AF ablation within 21 days or Anti-Arrhythmic Drug (AAD)