Clinical Research Directory

Inclusion Criteria: • Age between 18 and 45 years. Each participant will be enrolled in the study no earlier than the 20th week of pregnancy. Presence of at least one primary risk factor: * Pre-gestational hypertension. * Gestational hypertension. * Positive screening for preeclampsia. The presence of additional secondary risk factors (e.g., controlled type 1 or type 2 diabetes mellitus, obesity with BMI ≥ 30) may be recorded but is not sufficient on its own for inclusion in the study without meeting at least one primary criterion. Exclusion Criteria: * Uncontrolled diabetes and/or diabetes during the last 3 months prior to enrolment in this study. * Presence of a gynaecological disease that increases the risk of pregnancy complications, except for those conditions specifically listed in the inclusion criteria (e.g., chronic hypertension, gestational hypertension, pre-gestational hypertension, diabetes mellitus, obesity, or morbid obesity). * Participant with active malignant disease. * Participant with alcohol or drug abuse during the recruitment and during the trial course. * Participant enrolled in another clinical trial during the last 3 months prior to enrolling in this study. * Participants who, in the opinion of the study physician, may interfere with optimal participation in the study or may pose a risk to the participant. * Characteristics indicating a poor understanding of the study or characteristics that indicate the participant may have poor compliance with the study protocol. * Participants with severe or uncontrolled depression, which in the opinion of the study physician could influence participant's participation in the study; participants with stable depression and/or on a stable dose of an anti-depressant for at least three months may be included.