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RECRUITING
NCT07621549
NA

Exploring the Feasibility of Transcranial Ultrasound Stimulation in the Treatment of Schizophrenia

Sponsor: Far Eastern Memorial Hospital

View on ClinicalTrials.gov

Summary

1. The purpose of this study is to evaluate the safety and feasibility of transcranial ultrasound stimulation (TUS) treatment in patients with schizophrenia. Subjects are individuals diagnosed with schizophrenia who will receive non-invasive, low-intensity pulsed ultrasound stimulation targeting the hippocampus and its surrounding regions. Evaluations will be conducted before and after the treatment sessions, including electrocardiograms (ECG), blood biochemistry tests, psychiatric symptom assessments, depression level assessments, and cognitive function assessments. 2. The primary objective is to assess the safety of this intervention in patients with schizophrenia. The secondary objective is to explore whether the current stimulation parameters may lead to improvements in the assessed symptoms. Ultimately, this study aims to support the future application of low-intensity pulsed ultrasound as a potential intervention to alleviate symptoms of schizophrenia and improve patients' quality of daily life.

Key Details

Gender

All

Age Range

18 Years - 65 Years

Study Type

INTERVENTIONAL

Enrollment

80

Start Date

2025-06-01

Completion Date

2028-12-31

Last Updated

2026-06-02

Healthy Volunteers

No

Interventions

DEVICE

Transcranial Ultrasound Stimulation

Actual treatment in this group

DEVICE

Transcranial Ultrasound Stimulation

No actual treatment in this group

Locations (1)

Far Eastern Memorial Hospital

New Taipei City, Taiwan