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Peritoneal Transport With a New Bicarbonate-based Peritoneal Dialysis Solution Compared to Conventional Solution.
Sponsor: Karolinska Institutet
Summary
Cross-over study. Patients treated with peritoneal dialysis are investigated twice with a single 4h dwell study: once with Bicarbonate-Lactate solution as buffer (Physioneal TM) and once with conventional lactate PD solution (Dianeal TM). Radioidinated human serum albumin is used as a volume marker to assess ultrafiltration and frequent dialysis and blood sampling to assess peritneal transport of solutes and pH changes.
Key Details
Gender
All
Age Range
18 Years - Any
Study Type
INTERVENTIONAL
Enrollment
7
Start Date
1997-09-09
Completion Date
1997-11-13
Last Updated
2026-06-02
Healthy Volunteers
No
Interventions
Test of peritoneal fluid and solute transport using the relatvely new bicarbonate-lactate buffered peritoneal dialysis solution compared to convetional lactate based peritoneal dialysis solution
All patients were studied twice with a 4-h dwell study (one peritoneal dialysis dwell) about 7 days apart. The two arms represent different order of the two dwell studies.
Locations (1)
Research unit, renal medicine
Stockholm, Sweden