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Circadian Feeding and Reciprocal Scent Intervention in NICU
Sponsor: Inonu University
Summary
Objective: This study evaluated the effects of circadian-aligned feeding and reciprocal scent intervention on premature infants receiving mechanical ventilation and on postpartum depression levels in their mothers. Methods: In this randomized controlled trial, 75 premature infants and their mothers were assigned to reciprocal scent, circadian feeding, or control groups (n=25 each). Interventions were applied for 21 days. Outcomes included time to weaning from mechanical ventilation, weight gain, hydration status, breast milk production, and maternal Edinburgh Postnatal Depression Scale (EPDS) scores.
Official title: Babies Nourished by the Rhythm of Time: Maternal and Fetal Effects of Circadian Feeding and Reciprocal Scent Intervention in Neonatal Intensive Care
Key Details
Gender
All
Age Range
Any - 1 Year
Study Type
INTERVENTIONAL
Enrollment
150
Start Date
2025-10-01
Completion Date
2026-04-01
Last Updated
2026-06-03
Healthy Volunteers
No
Conditions
Interventions
Reciprocal Scent Intervention
Maternal-infant reciprocal scent exposure combined with circadian-aligned feeding.
Circadian-Aligned Feeding
Breast milk feeding synchronized with the timing of milk expression according to circadian rhythm.
Standard Care (in control arm)
Standard Care
Locations (1)
Sanliurfa Neonatal Intensive Care Unit
Sanliurfa, Turkey (Türkiye)