Tundra Space

Tundra Space

Clinical Research Directory

Browse clinical research sites, groups, and studies.

Back to Studies
ACTIVE NOT RECRUITING
NCT07623629
NA

The Impact of Using Different Final Irrigation Modes on Postoperative Pain Following Root Canal Treatment of Non-vital Mandibular First Molar With Periapical Lesion.

Sponsor: Future University in Egypt

View on ClinicalTrials.gov

Summary

The goal of this clinical trial is to learn which rinsing of root canals method works best to lower pain after a root canal in adults. The study focuses on participants aged 20 to 40 with an infection in a lower back tooth (mandibular first molar) and a small area of bone loss at the root tip. The main questions it aims to answer are: Does the type of tool used to rinse the tooth root canal change how much pain a participant feels after treatment? Does the cleaning method lower the number of painkillers a participant needs to take? Researchers will compare four different rinsing tools-ranging from a standard needle to advanced vacuum and vibration devices-to see if using suction and sound waves can lower pain levels. Participants will: Receive a complete root canal treatment in a single visit Be randomly assigned to one of four cleaning groups (standard rinse, vibration, vacuum, or a combination of both) Rate their pain on a scale of 0 to 10 at five specific times: before the visit, and at 6, 12, 24, and 48 hours after treatment Record how many painkiller tablets (Ibuprofen) they take during the two days following the procedure

Official title: The Impact of Using Different Final Irrigation Modes on Postoperative Pain Following Root Canal Treatment of Non-vital Mandibular First Molar With Periapical Lesion. "Randomized Controlled Trial"

Key Details

Gender

All

Age Range

20 Years - 40 Years

Study Type

INTERVENTIONAL

Enrollment

52

Start Date

2026-01-03

Completion Date

2026-10-01

Last Updated

2026-06-03

Healthy Volunteers

Yes

Interventions

PROCEDURE

root canal treatment

single visit root canal treatment with final irrigation protocol according to arm

Locations (1)

Future University in Egypt

Cairo, New Cairo, Egypt