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Privosegtor Investigation in Optic Neuropathies Efficacy Evaluation Research
Sponsor: Oculis
Summary
The goal of this clinical trial is to evaluate the safety and efficacy of privosegtor, a neuroprotective candidate, in patients diagnosed with optic neuritis (ON). Researchers will compare privosegtor and the standard of care (methylprednisolone) to a placebo and standard of care (methylprednisolone).
Official title: A Randomized, Double-masked, Placebo-controlled Study Assessing the Efficacy and Safety of Privosegtor (OCS-05) in Patients With Optic Neuritis (ON)
Key Details
Gender
All
Age Range
18 Years - 50 Years
Study Type
INTERVENTIONAL
Enrollment
210
Start Date
2026-05-28
Completion Date
2028-12
Last Updated
2026-08-14
Healthy Volunteers
No
Conditions
Interventions
Privosegtor
Privosegtor (OCS-05) 3 mg/kg/day IV for 5 treatment days
Methylprednisolone
Methylprednisolone 1 g/day IV for 5 treatment days
Placebo
0.9% sodium chloride (NaCl) solution IV for 5 treatment days
Locations (4)
Kahana Oculoplastic and Orbital Surgery
Livonia, Michigan, United States
Medical University of South Carolina, Storm Eye Institute
Charleston, South Carolina, United States
UT Southwestern Medical Center (Ophthalmology CRU)
Dallas, Texas, United States
Neuro-Eye Clinical Trials
Houston, Texas, United States