Clinical Research Directory

Inclusion Criteria: legally competent to provide written informed consent form prior to any study related procedures. * Subjects of either sex or aged 18 above * requires replacement of a single missing posterior tooth with adequate mesiodistal dimension (≥8 mm) * intact adjacent teeth on both sides with existing opposing tooth condition * good oral hygiene, plaque score \<25% bpe1 * adequate keratinized mucosa width (kmw) minimum 6 mm at the edentulous site * adequate bone volume to accommodate the planned dental implant placement of 5.5 mm diameter and 10 mm in length as verifified by Cone Beam Computed Tomography (CBCT) * adequate interoccusal distance (crown height space) of at least 6mm measured from alveolar crest to the occlusal table. Exclusion Criteria: Localized or generalized periodontitis * Presence of active acute infection * History of malignancy, radiotherapy or chemotherapy * Bone metabolic diseases (e.g.: osteogenesis imperfecta, Paget's disease) or current use of medications affecting bone metabolism * Untreated bruxism or parafunctional habits Docusign Envelope ID: FFD7C6C1-66CB-4359-9662-63230F769528 22 * Severe occlusal discrepancy * Any medical condition contraindicating implant placement or alter daily activities to a level consistent with ASA (American Society of Anesthesiologist) III classification (including cardiovascular, hepatic, renal, gastrointestinal, metabolic, neurologic, pulmonary, endocrine, autoimmune or psychiatric disorders) * Subjects in need of bone grafting at the site of intended implantation site. * Subjects that are pregnant