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Real-life Experience of Brentuximab Vedotin Plus CHP as First-line Treatment of CD30+ Peripheral T-cell Lymphomas in Spain
Sponsor: Grupo Español de Linfomas y Transplante Autólogo de Médula Ósea
Summary
The goal of this observational study is to evaluate how well brentuximab vedotin plus cyclophosphamide, doxorubicin, and prednisone (CHP) works and how safe it is when used as first-line treatment in adults with CD30-positive peripheral T-cell lymphoma in Spain during routine clinical care. The main questions this study aims to answer are: * How long do participants live without their lymphoma getting worse after starting treatment? * How well does this treatment reduce or eliminate the lymphoma? * How long do participants live after receiving this treatment? * What side effects do participants experience, including nerve problems and low white blood cell counts? Participants have already received brentuximab vedotin plus CHP as part of their usual medical care. Researchers will collect information from existing medical records to better understand treatment outcomes and safety in real-world clinical practice across multiple centers in Spain.
Key Details
Gender
All
Age Range
18 Years - Any
Study Type
OBSERVATIONAL
Enrollment
100
Start Date
2026-02-15
Completion Date
2027-05
Last Updated
2026-06-03
Healthy Volunteers
No
Conditions
Interventions
Brentuximab Vedotin Plus CHP
Brentuximab vedotin administered in combination with cyclophosphamide, doxorubicin, and prednisone (BV-CHP) as first-line treatment according to routine clinical practice. The treatment was prescribed by the treating physician as part of standard medical care and was not assigned or modified by the study
Locations (37)
Hospital Universitario A Coruña
A Coruña, A Coruña, Spain
Hospital Universitari Son Llàtzer
Palma de Mallorca, Balearic Islands, Spain
Hospital Universitari Son Espases
Palma de Mallorca, Balearic Islands, Spain
ICO Hospital Germans Trias i Pujol
Badalona, Barcelona, Spain
Hospital del Mar
Barcelona, Barcelona, Spain
Hospital Universitari Vall d'Hebron
Barcelona, Barcelona, Spain
Hospital Clínic de Barcelona
Barcelona, Barcelona, Spain
Hospital de la Santa Creu i Sant Pau
Barcelona, Barcelona, Spain
ICO Hospital Duran i Reynals
L'Hospitalet de Llobregat, Barcelona, Spain
Hospital Moisès Broggi
Sant Joan Despí, Barcelona, Spain
Hospital Universitario Marqués de Valdecilla
Santander, Cantabria, Spain
Hospital Universitario de Jerez
Jerez de la Frontera, Cádiz, Spain
Hospital Universitario Donostia
San Sebastián, Gipuzkoa, Spain
ICO Girona - Hospital Dr. Josep Trueta
Girona, Girona, Spain
Hospital Universitario Juan Ramón Jiménez
Huelva, Huelva, Spain
Hospital Universitario Doctor Negrín
Las Palmas de Gran Canaria, Las Palmas, Spain
Hospital Universitario Príncipe de Asturias
Alcalá de Henares, Madrid, Spain
Hospital del Sureste
Arganda, Madrid, Spain
Hospital Universitario Severo Ochoa
Leganés, Madrid, Spain
Hospital Universitario de La Princesa
Madrid, Madrid, Spain
Hospital Universitario Gregorio Marañón
Madrid, Madrid, Spain
Hospital Universitario Ramón y Cajal
Madrid, Madrid, Spain
Hospital Universitario 12 de Octubre
Madrid, Madrid, Spain
Hospital Universitario Rey Juan Carlos
Móstoles, Madrid, Spain
Hospital General Universitario Santa Lucía
Cartagena, Murcia, Spain
Hospital Universitario Morales Meseguer
Murcia, Murcia, Spain
Clínica Universidad de Navarra
Pamplona, Navarre, Spain
Hospital Álvaro Cunqueiro
Vigo, Pontevedra, Spain
Hospital Universitario San Agustín
Avilés, Principality of Asturias, Spain
Hospital Universitario Central de Asturias
Oviedo, Principality of Asturias, Spain
Hospital Universitario de Salamanca
Salamanca, Salamanca, Spain
Hospital Universitario de Canarias
San Cristóbal de La Laguna, Santa Cruz de Tenerife, Spain
Hospital General de Segovia
Segovia, Segovia, Spain
Hospital Universitario Virgen Macarena
Seville, Sevilla, Spain
ICO Hospital Universitari Joan XXIII
Tarragona, Tarragona, Spain
Hospital Francesc de Borja
Gandia, Valencia, Spain
Hospital Universitari i Politècnic La Fe
Valencia, Valencia, Spain