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NOT YET RECRUITING
NCT07625852
NA

Impact of Vertical vs. Transverse Closure on Outcomes of Laparoscopic Correction of Isthmocele

Sponsor: Minia University

View on ClinicalTrials.gov

Summary

Laparoscopic repair of Isthmocele aims to restore the anatomical integrity and physiological function of the lower uterine segment. * Vertical Closure: This technique involves closing the defect along the longitudinal axis of the uterus. Proponents suggest it may be more anatomically aligned with the muscle fibers of the lower uterine segment, potentially leading to stronger scar formation and reduced tension. * Transverse Closure: This technique involves closing the defect perpendicular to the long axis of the uterus. This approach is more commonly used during primary cesarean sections. Arguments for transverse closure in isthmocele repair include familiarity for surgeons and potentially less shortening of the lower uterine segment. However, the actual impact of these different closure methods on long-term outcomes such as defect recurrence, scar integrity, and fertility, remains largely unexplored in a randomized controlled trial setting.

Key Details

Gender

FEMALE

Age Range

18 Years - 45 Years

Study Type

INTERVENTIONAL

Enrollment

72

Start Date

2026-06-01

Completion Date

2027-06-01

Last Updated

2026-06-04

Healthy Volunteers

No

Conditions

Interventions

PROCEDURE

Vertical Closure

The hysterotomy defect will be closed in two layers using interrupted or continuous sutures along the longitudinal axis of the uterus

PROCEDURE

Transverse Closure

The hysterotomy defect will be closed in two layers using interrupted or continuous sutures perpendicular to the longitudinal axis of the uterus