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Piloting Novel Interventional Strategies to Improve Nicotine Pouches as a Substitute for Smoking
Sponsor: Medical University of South Carolina
Summary
Some people who smoke cigarettes try to switch to oral nicotine pouches but are not able to fully stop smoking. This study tests two new strategies for people who previously tried to switch using nicotine pouches. Participants who were unable to fully switch will either be asked to increase the nicotine strength of their pouches or to use a nicotine patch along with pouches. The goal of the study is to see whether these strategies are feasible, acceptable, and helpful, and to inform the design of larger future studies.
Key Details
Gender
All
Age Range
21 Years - Any
Study Type
INTERVENTIONAL
Enrollment
10
Start Date
2026-06
Completion Date
2026-10
Last Updated
2026-06-17
Healthy Volunteers
No
Conditions
Interventions
Nicotine replacement therapy patches
Nicotine replacement therapy patches will be dosed based on current cigarette smoking at the end of the parent trial.
Oral nicotine pouches
Zyn oral nicotine pouches will be provided in the flavor preference of the participant and dosed based on their randomization in the parent trial and randomization in the extension study.
Locations (1)
Medical Universtiy of South Carolina
Charleston, South Carolina, United States