Clinical Research Directory
Browse clinical research sites, groups, and studies.
Comparing the Outcome of Buccal Midazolam and Intramuscular Midazolam in Children Presenting With Seizures.
Sponsor: Pakistan Air Force (PAF) Hospital Islamabad
Summary
The goal of this clinical trial(Quasi Experimental) is to compare efficacy of oral midazolam over intra-muscular Midazolam in children suffering from seizures. The main question it aims to answer is: Does Buccal midazolam has a better efficacy as compared to intramuscular midazolam in children presenting with seizures? There will be two groups determined by randomisation and then one will be given buccal midazolam and other will will be administered IM Midazolam .The out come will be determined by the determining the cessation of seizures within 5 minutes duration achieved by administration of drug.
Official title: Comparison of Buccal Midazolam Versus Inter-muscular Midazolam in Control of Seizures
Key Details
Gender
All
Age Range
6 Months - 12 Years
Study Type
INTERVENTIONAL
Enrollment
90
Start Date
2022-01-15
Completion Date
2022-06-14
Last Updated
2026-06-15
Healthy Volunteers
No
Interventions
Midazolam
In group A, children were given intramuscular midazolam in the thigh at 0.05 ml/kg (maximum 1.6 ml). In group B, children were given buccal midazolam at 0.06 ml/kg (maximum 2 ml).
Locations (1)
PAF Hospital Islamabad
Islamabad, Capital, Pakistan