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Comparison of Rate of Tooth Movement Between MOPs vs MOPs & LLLT Combined
Sponsor: Riphah International University
Summary
Orthodontic treatment is often prolonged, requiring years to achieve desirable outcomes. The prolonged duration of treatment increases the risk of complications such as root resorption, periodontal damage, and patient non-compliance. To address these concerns, various methods have been explored to accelerate orthodontic tooth movement, including pharmacological agents, mechanical vibration, corticotomies, and minimally invasive techniques like Micro-Osteoperforations (MOPs) and Low-Level Laser Therapy (LLLT). Micro-Osteoperforations (MOPs) have gained popularity as a minimally invasive technique that enhances bone remodeling by inducing a localized inflammatory response, thereby accelerating tooth movement. Studies have shown that MOPs can effectively stimulate the expression of cytokines, increasing osteoclastic activity and facilitating rapid orthodontic tooth movement. However, the extent of its effectiveness varies among individuals, necessitating additional interventions to maximize efficiency. Low-Level Laser Therapy (LLLT), also known as photobiomodulation, is another promising adjunct in orthodontics. LLLT has been reported to enhance cellular activity, promote osteoblastic and osteoclastic function, and improve tissue healing, leading to accelerated tooth movement. Several studies suggest that LLLT alone can expedite orthodontic treatment, but its combination with MOPs has not been extensively explored. This study aims to compare the rate of orthodontic tooth movement between MOPs alone and MOPs combined with LLLT. By evaluating these two techniques, this research seeks to determine whether LLLT enhances the effectiveness of MOPs in accelerating tooth movement. The findings of this study could provide valuable insights into optimizing orthodontic treatment duration while minimizing potential risks and discomfort for patients.
Official title: Comparison of Rate of Tooth Movement Between Micro-osteoperforations Versus Micro-osteoperforations and Low Level Laser Therapy Combined
Key Details
Gender
All
Age Range
18 Years - 30 Years
Study Type
INTERVENTIONAL
Enrollment
33
Start Date
2026-06
Completion Date
2026-12
Last Updated
2026-06-04
Healthy Volunteers
Yes
Interventions
Micro-osteoperforation
MOPs will be performed using a sterile surgical instrument under local anesthesia, ensuring patient comfort during the procedure. Small perforations will be created in the alveolar bone adjacent to the tooth undergoing orthodontic movement along the long axis of the tooth with rule of 3, 3mm difference between three sites along the distal root of Canine. The intervention was repeated after 3 weeks interval for 9 weeks. GNI Mini Screws 1.8 x 8 mm
Low Level Laser Therapy and Micro-osteoperforations Combined
Woodpecker LX16 Plus Diode Laser (976± 20nm) will be applied at 5W and Frequency of 10000 Hz for 8 seconds producing a total of 8J Energy. MOPs will be performed using a sterile surgical instrument under local anesthesia, ensuring patient comfort during the procedure. Small perforations will be created in the alveolar bone adjacent to the tooth undergoing orthodontic movement along the long axis of the tooth with rule of 3, 3mm difference between three sites along the distal root of Canine. The intervention was repeated after 3 weeks interval for 9 weeks. GNI Mini Screws 1.8 x 8 mm
Locations (1)
Islamic International Dental Hospital
Islamabad, Punjab Province, Pakistan