Clinical Research Directory

1. Written informed consent for participation in the study; 2. Age between 18 and 45 years; 3. Bounded edentulous defects of the upper or lower jaw involving 1-2 teeth combined with soft tissue thickness deficiency around dental implants (\<2 mm); 4. Teeth without periodontal pathology, with probing depth not exceeding 3 mm throughout the gingival sulcus; 5. Satisfactory level of oral hygiene; 6. Absence of systemic diseases in the stage of exacerbation or decompensation. Non-inclusion criteria: 1. Patients who previously underwent connective tissue graft harvesting from the same donor site; 2. Patients with impacted third molars in the donor site area; 3. Presence of concomitant diseases in the stage of exacerbation or decompensation; 4. Patients with malignant neoplasms, as well as patients who underwent radiation therapy or chemotherapy within the previous 5 years; 5. Patients with a smoking history of more than 10 years. Exclusion Criteria: 1. Patient refusal to continue participation in the study; 2. Pregnant or breastfeeding women; 3. Patients with coagulation disorders (hemophilia, von Willebrand disease, or anticoagulant therapy); 4. Patients with diseases affecting soft tissue healing processes (insulin-dependent diabetes mellitus).