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Laparoscopic Versus Open Radical Hysterectomy in Early-Stage Cervical Cancer
Sponsor: Zagazig University
Summary
The study aims to compare laparoscopic-assisted radical hysterectomy with open radical hysterectomy in women with early-stage cervical cancer. A total of 60 patients diagnosed with FIGO stage IA1, IA2, and IB1 cervical cancer were enrolled and randomly assigned into two equal groups: laparoscopic surgery and open surgery. All patients underwent total hysterectomy, bilateral adnexectomy, and pelvic lymph node dissection. Perioperative outcomes were evaluated, including operative time, blood loss, complications, and hospital stay, as well as long-term oncological outcomes such as recurrence, recurrence-free survival, and overall survival. Patients were followed for up to three years postoperatively. The findings of this study aim to assess the safety, feasibility, and clinical effectiveness of laparoscopic-assisted surgery compared with the conventional open approach in the management of early-stage cervical cancer.
Official title: Radical Laparoscopic-assisted Hysterectomy Versus Open Radical Hysterectomy in Early-Stage Cervical Cancer: A Comparative Study
Key Details
Gender
FEMALE
Age Range
38 Years - 65 Years
Study Type
INTERVENTIONAL
Enrollment
60
Start Date
2021-03-01
Completion Date
2024-01-31
Last Updated
2026-06-04
Healthy Volunteers
No
Conditions
Interventions
Laparoscopic Radical Hysterectomy
In this procedure, a minimally invasive laparoscopic-assisted radical hysterectomy is performed, including dissection of the pelvic lymph nodes and closure of the vaginal stump with an endoscopic stapler.
Open Radical Hysterectomy
A standard open abdominal radical hysterectomy includes dissection of the pelvic lymph nodes and the closure of the vaginal stump.
Locations (1)
Zagazig University Hospitals
Zagazig, Sharqia Province, Egypt