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RECRUITING
NCT07629154

Smart Discharges for Older Children

Sponsor: University of British Columbia

View on ClinicalTrials.gov

Summary

This study is an observational multi-country cohort study that aims to build algorithms that can identify children between 5 and 16 years of age admitted for proven or suspected sepsis who are at risk of mortality after they are discharged in East Africa. In low- and middle-income countries, about 5% of children discharged after hospitalization for sepsis will die in the weeks after returning home. Doctors and parents are often unaware of this period of vulnerability and are poorly equipped to identify or handle this critical situation. This project builds on past work that developed and evaluated models and the Smart Discharges program to predict, during hospitalization, an individual child's risk of recurrent illness and mortality, as well as to provide additional post-discharge support to at-risk children. Participants will be enrolled from facilities once they are admitted, collecting clinical and social variables. They will then be followed until 6 months post-discharge to understand what happens to them after they return home. This data will be evaluated to identify which variables collected at facilities can be predictive of mortality and recurrent illness after discharge.

Official title: Smart Discharges for Older Children: A Cohort Study to Develop Prognostic Algorithms for Post-discharge Readmission and Mortality Among Children Over 5 Years of Age

Key Details

Gender

All

Age Range

5 Years - 16 Years

Study Type

OBSERVATIONAL

Enrollment

4000

Start Date

2024-01-02

Completion Date

2027-04

Last Updated

2026-06-05

Healthy Volunteers

Not specified

Conditions

Interventions

OTHER

No Intervention: Observational Cohort

This is a non-interventional study

Locations (7)

University of California, San Francisco

San Francisco, California, United States

Weill Cornell Medicine

Ithaca, New York, United States

University of Washington

Seattle, Washington, United States

BC Children's Hospital Research Institute

Vancouver, British Columbia, Canada

The Rwanda Paediatric Association

Kigali, Rwanda

Catholic University Of Health And Allied Sciences

Mwanza, Tanzania

WALIMU

Mbarara, Uganda