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Smart Discharges for Older Children
Sponsor: University of British Columbia
Summary
This study is an observational multi-country cohort study that aims to build algorithms that can identify children between 5 and 16 years of age admitted for proven or suspected sepsis who are at risk of mortality after they are discharged in East Africa. In low- and middle-income countries, about 5% of children discharged after hospitalization for sepsis will die in the weeks after returning home. Doctors and parents are often unaware of this period of vulnerability and are poorly equipped to identify or handle this critical situation. This project builds on past work that developed and evaluated models and the Smart Discharges program to predict, during hospitalization, an individual child's risk of recurrent illness and mortality, as well as to provide additional post-discharge support to at-risk children. Participants will be enrolled from facilities once they are admitted, collecting clinical and social variables. They will then be followed until 6 months post-discharge to understand what happens to them after they return home. This data will be evaluated to identify which variables collected at facilities can be predictive of mortality and recurrent illness after discharge.
Official title: Smart Discharges for Older Children: A Cohort Study to Develop Prognostic Algorithms for Post-discharge Readmission and Mortality Among Children Over 5 Years of Age
Key Details
Gender
All
Age Range
5 Years - 16 Years
Study Type
OBSERVATIONAL
Enrollment
4000
Start Date
2024-01-02
Completion Date
2027-04
Last Updated
2026-06-05
Healthy Volunteers
Not specified
Conditions
Interventions
No Intervention: Observational Cohort
This is a non-interventional study
Locations (7)
University of California, San Francisco
San Francisco, California, United States
Weill Cornell Medicine
Ithaca, New York, United States
University of Washington
Seattle, Washington, United States
BC Children's Hospital Research Institute
Vancouver, British Columbia, Canada
The Rwanda Paediatric Association
Kigali, Rwanda
Catholic University Of Health And Allied Sciences
Mwanza, Tanzania
WALIMU
Mbarara, Uganda