Clinical Research Directory

Measuring Blood Vessel Density in the Optic Nerve of Multiple Sclerosis Patients With OCTA

Sponsor: Fayoum University

Summary

The goal of this observational study is to learn about the effect of multiple sclerosis on the blood flow of the optic nerve of affected patients compared to normal subjects by OCTA. The main question it aims to answer is: 1. Does MS change the blood flow in the optic nerve? 2. If it does, can measuring this blood flow be used as a simple sign (a biomarker) to help doctors understand and manage MS? We used a quick and painless eye scan called Optical Coherence Tomography Angiography (OCTA). This special scan takes detailed pictures of the blood vessels in the optic nerve without needing any injections. We performed this scan on two groups of people: one group with MS and one group without MS, and then compare the results. In simple terms, why is this important? If we can show that MS affects the optic nerve blood vessels, it could give us a new, quick way to monitor the disease and see how it is progressing, just by doing a simple eye scan.

Official title: Quantitative OCT Angiography Differences in Optic Nerve Vascular Density in Multiple Sclerosis: A Case-Control Study

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