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Efficacy of Alpha Lipoic Acid Combined With Myo-Inositol in Non-Diabetic PCOS Patients
Sponsor: Beni-Suef University
Summary
This study evaluates the efficacy of alpha-lipoic acid combined with myo-inositol, with or without metformin, in improving menstrual regularity and ovulation in non-diabetic women with polycystic ovary syndrome (PCOS). The study also assesses metabolic, hormonal, and clinical outcomes.
Official title: A Randomized Controlled Trial Evaluating the Efficacy of Alpha Lipoic Acid Combined With Myo-Inositol With or Without Metformin in Non-Diabetic Women With Polycystic Ovary Syndrome
Key Details
Gender
FEMALE
Age Range
21 Years - 40 Years
Study Type
INTERVENTIONAL
Enrollment
180
Start Date
2026-03-10
Completion Date
2026-12
Last Updated
2026-06-05
Healthy Volunteers
No
Conditions
Interventions
Myo-inositol
Myo-inositol administered orally at a dose of 2 g twice daily for 6 months.
Folic Acid
Folic acid administered orally at a dose of 200 micrograms twice daily for 6 months.
Alpha Lipoic Acid
Alpha-lipoic acid administered orally at a dose of 600 mg once daily for 6 months.
Metfomin
Metformin administered orally starting at 500 mg once daily and titrated over two weeks to a maximum dose of 1500 mg/day (500 mg three times daily), taken after meals for 6 months.
Locations (1)
Faculty of Medicine, Cairo University
Cairo, Cairo Governorate, Egypt