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Nebulized AER101 in Pre-op NSCLC
Sponsor: University of Oklahoma
Summary
The primary objective of this pilot study is to determine if AER101 can decrease glycolysis in non-small cell lung cancer (NSCLC). Glycolysis is the process cells use to break down sugar (glucose) into a smaller substance in the fluid part inside the cell. Many lung cancers begin in bronchi, bronchioles and alveoli cells surrounding the airways, which enables nebulization to deposit AER101 on lung tumors. Participants in the study will self-administer AER101 via a hand-held personal nebulizer three times per day (dosing at least 4 hours apart) for 14 days prior to undergoing surgery for lung cancer.
Official title: Nebulized AER101 to Inhibit Glycolysis for Pre-Operative Non-small Cell Lung Cancer (NSCLC)
Key Details
Gender
All
Age Range
18 Years - 100 Years
Study Type
INTERVENTIONAL
Enrollment
5
Start Date
2026-06
Completion Date
2027-06
Last Updated
2026-06-08
Healthy Volunteers
No
Interventions
AER101
Nebulization of AER101
Locations (2)
OU Medical Center Hospital
Oklahoma City, Oklahoma, United States
Stephenson Cancer Center
Oklahoma City, Oklahoma, United States