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MAGNEsium With meToprolol for Rate Control In Atrial Fibrillation
Sponsor: Wake Forest University Health Sciences
Summary
The purpose of this research study is to find out if the use of magnesium in addition to Metoprolol, a rate controlling medication that you would be offered in the Emergency Department today unrelated to this study, will help reduce your high heart rate (rapid ventricular response).
Official title: MAGNEsium With meToprolol for Rate Control In Atrial Fibrillation (MAGNETIC-AF)
Key Details
Gender
All
Age Range
18 Years - Any
Study Type
INTERVENTIONAL
Enrollment
196
Start Date
2026-06
Completion Date
2028-12
Last Updated
2026-06-08
Healthy Volunteers
No
Interventions
Magnesium Sulfate 2g
Magnesium Sulfate 2g for the treatment of atrial fibrillation or atrial flutter with rapid ventricular response (AFF RVR)
Magnesium Sulfate 4g
Magnesium Sulfate 4g for the treatment of atrial fibrillation or atrial flutter with rapid ventricular response (AFF RVR)
Saline (0.9% NaCl)
The control group will receive a bolus of normal saline of the same volume and infused over 15 minutes.
Locations (1)
Advocate Christ Medical Center Emergency Department (ACMC ED)
Oak Lawn, Illinois, United States