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Effects of Standard and Modified Z-Trendelenburg Positions on Cerebral Oxygenation and Optic Nerve Sheath Diameter
Sponsor: Ankara Etlik City Hospital
Summary
The purpose of this study is to compare the effects of the standard Trendelenburg position and the modified Z-Trendelenburg position on cerebral oxygenation and optic nerve sheath diameter (ONSD) in patients undergoing laparoscopic surgery. The prolonged use of the standard Trendelenburg position combined with pneumoperitoneum can increase intracranial pressure and affect cerebral blood flow. In this study, researchers will use non-invasive methods, including Near-Infrared Spectroscopy (NIRS) to monitor regional cerebral oxygenation, and ocular ultrasonography to measure ONSD as an indicator of intracranial pressure changes. The main goal is to determine whether the modified Z-Trendelenburg position serves as a safer physiological alternative by reducing these potential adverse effects compared to the standard position.
Official title: Comparison of the Effects of Standard Trendelenburg and Modified Z Trendelenburg Positions on Cerebral Oxygenation (NIRS) and Optic Nerve Sheath Diameter in Laparoscopic Gynecological Cases
Key Details
Gender
FEMALE
Age Range
18 Years - 80 Years
Study Type
OBSERVATIONAL
Enrollment
70
Start Date
2026-03-06
Completion Date
2026-05-18
Last Updated
2026-06-08
Healthy Volunteers
Yes
Conditions
Interventions
Standard Trendelenburg Position
Placement of the patient in the traditional straight head-down tilt position required for laparoscopic surgical access and pneumoperitoneum
Modified Z-Trendelenburg Position
Placement of the patient in a modified head-down tilt position combined with leg flexion
Locations (1)
Ankara Etlik City Hospital
Ankara, Ankara, Turkey (Türkiye)