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Desloratadine as Adjunct Therapy for Rheumatoid Arthritis
Sponsor: Horus University
Summary
Rheumatoid arthritis is a chronic inflammatory disease that causes joint pain, swelling, and reduced physical function. Although standard disease-modifying antirheumatic drugs are effective for many patients, some individuals continue to have active disease. The purpose of this study is to evaluate the effectiveness and safety of adding desloratadine to standard therapy in patients with active rheumatoid arthritis. Participants will receive either desloratadine or placebo in addition to their usual treatment. The study will assess changes in disease activity and inflammatory markers over a follow-up period of approximately 12 weeks. The results of this study may help determine whether desloratadine could be a useful add-on treatment option for patients with rheumatoid arthritis.
Official title: Effect of Desloratadine as Add-On Therapy in Rheumatoid Arthritis
Key Details
Gender
All
Age Range
18 Years - 60 Years
Study Type
INTERVENTIONAL
Enrollment
60
Start Date
2026-05-23
Completion Date
2027-01
Last Updated
2026-06-08
Healthy Volunteers
No
Interventions
Desloratadine 5 mg
Desloratadine administered orally as add on therapy to standard disease modifying antirheumatic drugs.
Placebo
Matching placebo administered orally as add on therapy to standard disease modifying antirheumatic drugs.
Locations (1)
Faculty of medicine, Mansoura University
Al Mansurah, Egypt