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COMPLETED
NCT07636317
NA

Letrozole Plus Misoprostol Versus Misoprostol Only in Induction of Missed Abortion

Sponsor: Sohag University

View on ClinicalTrials.gov

Summary

This study aimed to evaluate the effect of letrozole plus misoprostol to terminate non-viable pregnancies in first trimester compared with the use of misoprostol alone.

Official title: Letrozole Plus Misoprostol Versus Misoprostol Only in Induction of Missed Abortion: A Randomized Controlled Trial

Key Details

Gender

FEMALE

Age Range

18 Years - 45 Years

Study Type

INTERVENTIONAL

Enrollment

400

Start Date

2025-06-14

Completion Date

2026-03-01

Last Updated

2026-06-09

Healthy Volunteers

No

Interventions

DRUG

Letrozole + Misoprostol

Patients received 10 mg of Letrozole daily for three days, subsequently receiving 800 µg of Misoprostol every three hours via vaginal or sublingual routes.

DRUG

Misoprostol

Patients received only 800 µg of Misoprostol.

Locations (1)

Sohag University

Sohag, Egypt