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Effect of Individualized Positive End-expiratory Pressure (PEEP) in Patients Who Have an Intrinsic PEEP During One-lung Ventilation
Sponsor: Samsung Medical Center
Summary
This study investigates the effects of three extrinsic PEEP settings-5 cmH2O, 0 cmH2O, and an individualized PEEP (70% of the measured intrinsic PEEP)-on intrinsic PEEP and hemodynamic stability in patients with intrinsic PEEP undergoing lung resection surgery, using a randomized, crossover design.
Official title: Effects of Individualized Positive End-expiratory Pressure (PEEP) on Intrinsic PEEP and Stroke Volume During One-lung Ventilation: a Single-center, Randomized Crossover Study
Key Details
Gender
All
Age Range
19 Years - 100 Years
Study Type
INTERVENTIONAL
Enrollment
48
Start Date
2026-06-01
Completion Date
2027-05-31
Last Updated
2026-06-10
Healthy Volunteers
No
Interventions
PEEP0
PEEP 0 (zero) means off-PEEP on the anesthesia machine.
PEEP5
PEEP5 means setting the PEEP to 5 cmH2O on the anesthesia machine.
PEEPi
PEEPi (individualized PEEP) means setting the PEEP to 70% of intrinsic PEEP on the anesthesia machine.