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PotenziaMente: A Digital Executive Function Training Intervention for Healthy Aging in the Elderly Population
Sponsor: Università degli Studi di Trento
Summary
The study, entitled "PotenziaMente: Cognitive Training in Aging," is a clinical trial designed to evaluate the effectiveness of an individualized tablet-based cognitive training program targeting executive functions (e.g., planning, cognitive flexibility, and problem solving) in healthy older adults. Executive functions are higher-order cognitive processes that support adaptive functioning in daily life and influence other cognitive domains, such as memory. The primary aim of the study is to enhance cognitive performance, specifically executive abilities, in neurologically healthy adults aged 65 to 75 years. A secondary aim is to compare whether there are differences in the effects of two different delivery modalities of the same cognitive training program: home-based self-administration via tablet versus supervised tablet-based training in the presence of a trained researcher. Participants will undergo cognitive assessments at baseline (pre-training), immediately after the intervention (post-training), and at a 3-month follow-up. This is a randomized parallel-group interventional clinical trial with no masking. Participants are randomly assigned to one of two groups: a home-based cognitive training condition, in which they perform an individualized tablet-based cognitive training program targeting executive functions independently at home via a tablet application without direct supervision, or a supervised cognitive training condition, in which they perform the same individualized tablet-based cognitive training under the supervision of a trained researcher in a controlled environment. The intervention consists of two sessions per week, 1 hour per session, for 4 consecutive weeks, delivered via tablet-based exercises. The study uses a parallel assignment model with a prospective time perspective and a primary purpose of treatment (cognitive enhancement / prevention of cognitive decline). The primary outcome is the change in executive functions from baseline to post-intervention, assessed using standardized neuropsychological tests. Secondary outcomes include between-group differences (home-based vs supervised) in executive function performance, changes in global cognitive functioning from baseline to post-intervention, and maintenance of cognitive effects at the 3-month follow-up.
Key Details
Gender
All
Age Range
65 Years - 75 Years
Study Type
INTERVENTIONAL
Enrollment
60
Start Date
2024-09-17
Completion Date
2026-09
Last Updated
2026-06-10
Healthy Volunteers
Yes
Conditions
Interventions
Remote Cognitive Training
A 4-week tablet-based cognitive training intervention targeting executive functions in healthy older adults. Participants complete 2 individual training sessions per week (1 hour each), delivered remotely via email and performed independently at home using a tablet. The intervention focuses on enhancing executive functions, including planning, cognitive flexibility, and problem solving, with the aim of improving overall cognitive performance in daily life functioning.
Supervised In-Person Cognitive Training
A 4-week tablet-based cognitive training intervention targeting executive functions in healthy older adults. Participants complete 2 individual training sessions per week (1 hour each), delivered in-person under the supervision of a trained researcher in a controlled environment. The intervention focuses on enhancing executive functions, including planning, cognitive flexibility, and problem solving, with the aim of improving overall cognitive performance in daily life functioning.
Locations (1)
Centro Interdipartimentale Mente/Cervello - CIMeC
Rovereto, Trento, Italy