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Key Diagnostic & Therapeutic Technologies for Severe Acute High Altitude Disease (SAHAD): Integration and Application
Sponsor: Tibet Autonomous Region People's Hospital
Summary
This study aims to establish a key technical system for the diagnosis and treatment of severe acute mountain sickness based on real-world clinical data in Xizang, develop standardized diagnosis and treatment protocols and an intelligent early warning model, validate its efficacy through multicenter studies, and innovate diagnostic and therapeutic technologies. It will achieve early identification, precise diagnosis, standardized treatment, and intelligent warning of severe acute mountain sickness, comprehensively improving its prevention, control and treatment success rate.
Official title: Integration and Application Demonstration of Key Diagnosis and Treatment Technologies for Severe Acute High Altitude Disease
Key Details
Gender
All
Age Range
18 Years - 75 Years
Study Type
INTERVENTIONAL
Enrollment
3035
Start Date
2026-07-01
Completion Date
2028-12-31
Last Updated
2026-06-10
Healthy Volunteers
Yes
Interventions
Multicenter study of HAPE：CPAP or BiPAP Group
Traditional treatment plus CPAP or BiPAP
Multicenter study of HAPE group：NO Group
Traditional treatment plus inhaled nitric oxide therapy (20-40 ppm, continuous administration for 12-24 hours)
Protocol for Proteomics and Peptidomics Study of HAPE：Case Group
40 patients clinically diagnosed with HAPE. Peripheral venous blood samples were collected during the acute onset stage and prior to any effective intervention.
Locations (1)
Xizang Autonomous Region People's Hospital
Lhasa, Tibet, China