Clinical Research Directory

* Patients admitted with cardiogenic shock to the University hospital Basel (diagnosis at the time of admission) or development of cardiogenic shock during the hospital stay * Age ≥18 years * Provision of written ICF * Clinical diagnosis of cardiogenic shock. * impaired organ perfusion due to primary cardiac dysfunction, * persistent systolic blood pressure (SBP) \<90 mmHg for ≥30 minutes, or the need for vasopressors, inotropes, or mechanical circulatory support (MCS) to maintain adequate perfusion and * evidence of systemic hypoperfusion with arterial lactate ≥2 mmol/L or venous lactate ≥3 mmol/l and ≥1 of the following: * Cold or clammy extremities * Altered mental status * Reduced urine output * Signs of volume overload or congestion (on clinical exam, imaging, or invasive monitoring) * Patients with normotensive cardiogenic shock (SBP ≥90 mmHg without vasopressors or MCS) may also be included if clear signs of hypoperfusion (arterial lactate ≥2 mmol/L or venous lactate ≥3 mmol/l) and cardiac dysfunction are present and alternative causes are excluded Exclusion criteria: * Age \<18 years * Refusal to provide informed consent by the patient or their legally authorized representative