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The ADVANCE (Assay Development and Validation for Pre-Natal and Obstetric Conditions) Study is the Largest U.S.-Based Prospective Study Demonstrating a Circulating Fetal Cell (CFC) Based Approach to Non-invasive Fetal Risk Assessment
Sponsor: BillionToOne Inc.
Summary
The goal of the ADVANCE (Assay Development and Validation for Pre-Natal and Obstetric Conditions) study is to compare the concordance of results of a novel non-invasive circulating fetal cell (CFC) assay to the results of prenatal invasive diagnostic testing or postnatal genetic and clinical diagnosis of the resulting neonate. This is a prospective study of pregnant individuals.
Official title: ADVANCE Study: Assay Development and Validation for Pre-Natal and Obstetric Conditions
Key Details
Gender
FEMALE
Age Range
Any - Any
Study Type
OBSERVATIONAL
Enrollment
1000
Start Date
2026-01-10
Completion Date
2028-06
Last Updated
2026-10-15
Healthy Volunteers
No
Conditions
Locations (9)
Valley Perinatal Services
Phoenix, Arizona, United States
Brar Practice
Riverside, California, United States
San Gabriel Valley Perinatal Medical Group
West Covina, California, United States
Sarasota Memorial Health Care System
Sarasota, Florida, United States
Pediatrix Medical Group of Georgia
Atlanta, Georgia, United States
Woman's Hospital
Baton Rouge, Louisiana, United States
Carnegie Imaging for Women
New York, New York, United States
UT Physicians Maternal-Fetal Medicine
Houston, Texas, United States
Pediatrix Medical Group
Houston, Texas, United States