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NOT YET RECRUITING
NCT07643961
NA

Outpatient Versus Inpatient Management of Mild Acute Pancreatitis

Sponsor: Center for Traumatology and Major Burns, Ben Arous

View on ClinicalTrials.gov

Summary

Acute pancreatitis is a sudden inflammation of the pancreas that causes severe abdominal pain. Most cases are mild and get better within a few days with basic supportive treatment such as fluids and pain relief. Currently, all patients with acute pancreatitis are admitted to hospital, even those with a very low risk of complications. This study will test whether patients with mild acute pancreatitis can be safely sent home with close follow-up (telephone calls on days 1, 2, and 3 after discharge and a clinic visit on day 4) instead of staying in hospital. Patients will be randomly assigned to either home management or standard hospitalization. We will compare the rate of treatment failure at 30 days between the two groups. We expect that home management will be as safe as hospitalization, while being more convenient for patients and less costly for the health system.

Official title: Outpatient Versus Inpatient Management of Mild Acute Pancreatitis: A Randomised Controlled Non-Inferiority Trial

Key Details

Gender

All

Age Range

18 Years - Any

Study Type

INTERVENTIONAL

Enrollment

150

Start Date

2026-07-01

Completion Date

2027-03-31

Last Updated

2026-07-10

Healthy Volunteers

No

Interventions

OTHER

Outpatient Management (Group A)

Early discharge from the emergency department after 4-6 hours of observation, with structured teleconsultation follow-up on Days 1, 2, and 3, in-person review on Day 4, unrestricted emergency department access, and 30-day outcome assessment.

OTHER

Standard Inpatient Management (Group B)

Conventional ward admission with daily monitoring, intravenous supportive care, and discharge based on clinical improvement.

Locations (1)

Traumatology and great burns center

Ben Arous, Tunisia, Tunisia