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RECRUITING
NCT07644338
NA

The Efficacy and Safety of Temporal Interference Stimulation in the Treatment of Post-Traumatic Stress Disorder

Sponsor: Shanghai Mental Health Center

View on ClinicalTrials.gov

Summary

This study aims to evaluate the efficacy and safety of Temporal Interference (TI) stimulation in treating patients with post-traumatic stress disorder (PTSD) and to explore its potential neural mechanisms using magnetic resonance imaging (MRI) ,magnetoencephalography(MEG),electroencephalography (EEG).

Key Details

Gender

All

Age Range

18 Years - 50 Years

Study Type

INTERVENTIONAL

Enrollment

5

Start Date

2026-06-08

Completion Date

2027-06

Last Updated

2026-06-12

Healthy Volunteers

No

Interventions

DEVICE

TI stimulation device (nerviox-1000)

The TI stimulation device delivers temporally interfering electrical fields with a 160 Hz envelope frequency, generated by high-frequency carrier waves (2000 Hz and 2160 Hz). Stimulation is applied for 20 minutes per session, with a peak current of 3-4 mA per channel, adjusted based on individual tolerance. The stimulation target is the bilateral amygdala. Stimulation is administered twice daily, with the treatment phase lasting 7 consecutive days.

Locations (1)

Shanghai Mental Health Center

Shanghai, China