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Efficacy and Safety of a Topical Botanical Extract Formulation for Skin Barrier Repair
Sponsor: L'Oreal
Summary
This is a single-center, double-blinded, placebo-controlled, prospective clinical study designed to evaluate the skin barrier repair efficacy and local tolerance of topical cosmetic formulations containing a botanical extract. Skin barrier challenge is induced via standardized tape stripping on the volar forearm of healthy subjects. The study will evaluate and compare the repair kinetics of two concentrations of the active formulation, a vehicle, and an untreated control zone over a 14-day application period.
Official title: A Single-Center, Double-Blinded, Randomized, Placebo-Controlled, Prospective Study to Evaluate the Efficacy and Safety of a Botanical Extract in Skincare Formulations for Skin Barrier Repair on Healthy Volunteers
Key Details
Gender
FEMALE
Age Range
35 Years - 60 Years
Study Type
INTERVENTIONAL
Enrollment
35
Start Date
2025-10-13
Completion Date
2026-07-25
Last Updated
2026-06-16
Healthy Volunteers
Yes
Conditions
Interventions
Cosmetic Topical Product A
Topical skincare formulation containing Botanical Extract (Concentration A). Applied twice daily for 14 days.
Cosmetic Topical Product B
Topical skincare formulation containing Botanical Extract (Concentration B). Applied twice daily for 14 days.
Vehicle
Topical formulation base (identical to investigational products but without the active botanical extract). Applied twice daily for 14 days.
Locations (1)
L'OREAL
Shanghai, China