Clinical Research Directory
Browse clinical research sites, groups, and studies.
Microvasculature Ultrasound Super-resolution in Transplant Delayed Graft Function
Sponsor: Roderick Tan
Summary
This pilot study is testing a new ultrasound imaging method called Super-Resolution Ultrasound (SRU) to look at blood flow and tiny blood vessels in transplanted kidneys in very detailed images after kidney transplant surgery. The goal is to see whether changes in the kidney's small blood vessels can help predict how well the transplanted kidney will work early after transplant, including whether delayed graft function may occur. Investigators hope this technique can become a safe, noninvasive way to evaluate transplanted kidneys without needing as many invasive biopsies. It may also help doctors better assess donor kidneys at higher-risk of suboptimal functioning.
Key Details
Gender
All
Age Range
18 Years - Any
Study Type
OBSERVATIONAL
Enrollment
40
Start Date
2026-06-01
Completion Date
2028-06-30
Last Updated
2026-06-12
Healthy Volunteers
No
Conditions
Interventions
Ultrasound contrast agent (Contrast-enhanced ultrasound)
Super-resolution ultrasound using lipid microsphere contrast
Optison (Perflutren Protein-Type A Microspheres Injectable Suspension)
Approved drug or biologic being evaluated for a new indication, population, route of administration, or dosage level not specified in the FDA approved labeling for kidney imaging.
Lumason® contrast agent
Approved drug or biologic being evaluated for a new indication, population, route of administration, or dosage level not specified in the FDA approved labeling for kidney imaging.
DEFINITY®
Approved drug or biologic being evaluated for a new indication, population, route of administration, or dosage level not specified in the FDA approved labeling for kidney imaging.
Locations (1)
University of Pittsburgh Medical Center
Pittsburgh, Pennsylvania, United States