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The Impact of Ventilator Synchrony on Muscle Relaxant Consumption and Surgeon Satisfaction During Laparoscopic Cholecystectomy.
Sponsor: Hitham Mohammed Aly Elsayed
Summary
The goal of this clinical trial is to investigate the Impact of adding SIMV Synchronization to our standard PCV-VG mode of ventilation on muscle relaxant consumption, the frequency of relaxant top-ups and surgeon satisfaction during Laparoscopic Cholecystectomy surgeries in ASA I\&II. The main question it aims to answer is do Ventilator synchrony (PCV-VG+SIMV) reduces muscle relaxant consumption and improves surgeon satisfaction by minimizing the perception of inadequate paralysis? Primary hypothesis: Ventilator synchrony (PCV-VG+SIMV) reduces muscle relaxant consumption and improves surgeon satisfaction by minimizing the perception of inadequate paralysis. Primary outcome; 1. Compare total intraoperative rocuronium consumption (mg/kg) between PCV-VG and PCV-VG + SIMV 2. To determine the frequency of additional muscle relaxant requests
Key Details
Gender
All
Age Range
18 Years - 60 Years
Study Type
INTERVENTIONAL
Enrollment
60
Start Date
2026-08
Completion Date
2029-06
Last Updated
2026-06-15
Healthy Volunteers
No
Interventions
Non-Synchronized Group (Control)
Ventilation managed using PCV-VG mode of ventilation
Synchronized group
Ventilation managed using PCV-VG plus SIMV (a mixed mode that supports patient-ventilator synchrony)
Locations (1)
King Fahd University Hospital
Khobar, Eastern Province, Saudi Arabia