Clinical Research Directory
Browse clinical research sites, groups, and studies.
Rhythm Psychophysics With Parkinson's Patients
Sponsor: McMaster University
Summary
The goal of this interventional study is to understand how the rhythmic abilities of individuals in the early stages of Parkinson's Disease (PD) are impacted by their levels of dopamine. The main questions it aims to answer are: * Does dopamine shelter the ability to generate and maintain a regular tapping rhythm in the presence of disrupting sensory information? * Does dopamine allow the adaptation of tapping speed in the presence of changing sensory information? * Is the engagement of the motor system useful to improve the detection of changes in the tempo of sensory information? Participants will be asked to perform a battery of simple rhythmic tasks On and Off medication to evaluate the effect of dopamine on their rhythmic skills.
Key Details
Gender
All
Age Range
40 Years - 80 Years
Study Type
INTERVENTIONAL
Enrollment
34
Start Date
2026-09-01
Completion Date
2027-10-31
Last Updated
2026-06-15
Healthy Volunteers
No
Conditions
Interventions
Withholding Levodopa
Participants will have to withhold Levodopa medication 12 h before one of two experimental sessions.
Locations (1)
Psychology Building
Hamilton, Ontario, Canada