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Comparison Immune Response in Paravertebral and Erector Spinal Plane Block in Breast Cancer Patients
Sponsor: Clinical Hospital Center Rijeka
Summary
The goal of this clinical trial is to find the difference in immune response between two types of regional anesthesia in female patients suffering from breast cancer. The main question it aims to answer is there a difference in the immune response between paravertebral block and erector spinal plane block. Hypothresis of the study is that paravertebral block with propofol induces less immune response in surgical treatment of breast cancer patients than erector spinal plane block. Participants will be asked to sign the informant consent. They will be given either paravertebral block or erector spinae plane block with general anesthesia using propofol. Their venous blood will be taken 1 hour prior surgery and 24 and 48 hours after surgery.
Official title: Immunologic Response in Breast Cancer Before and After Application of Paravertebral and Erector Spinae Plane Block
Key Details
Gender
FEMALE
Age Range
18 Years - 70 Years
Study Type
INTERVENTIONAL
Enrollment
56
Start Date
2026-06-15
Completion Date
2027-04-15
Last Updated
2026-06-15
Healthy Volunteers
No
Conditions
Interventions
Regional Anesthetic Injection
Draw of venous blood and application of paravertebral and erector spinae plane block
Blood draw for the laboratory assessment
Draw of venous blood 24 hours after surgery
Blood draw for the laboratory assessment
Blood draw 48 hours after surgery