Clinical Research Directory

Inclusion Criteria: Cohort A 1. ≥18 years of age at the time of recruitment 2. IgAN diagnosis confirmed with a renal biopsy 3. Episodic/Intermittent Loin Pain (defined as pain at least once every 6 months) 4. Have the capacity to consent to the study Cohort B 1\) ≥18 years of age at the time of recruitment 2) IgAN diagnosis confirmed with a renal biopsy 3) No history of loin pain 4) Have the capacity to consent to the study Exclusion Criteria: Cohort A 1. Constant loin pain 2. Infrequent loin pain (no pain experienced in the last 6 months) 3. Inability to differentiate loin pain from back pain 4. Other renal diseases 5. Therapies that interfere with immune-mediation like steroids and complement inhibitors 6. Kidney transplant recipients 7. Current participation in an interventional study that may affect kidney function 8. Patients on dialysis 9. Patients with implants that are not MRI-safe (pacemakers, implantable defibrillators, cochlear implants, some shunts, neurostimulators, some aneurysm clips, etc.) Cohort B 1. Other renal diseases 2. Therapies that interfere with immune-mediation like steroids and complement inhibitors 3. Kidney transplant recipients 4. Current participation in an interventional study that may affect kidney function 5. Patients on dialysis 6. Patients with conditions/implants that are not MRI-compatible (claustrophobia, pacemakers, implantable defibrillators, cochlear implants, some shunts, neurostimulators, some aneurysm clips, etc.)