Clinical Research Directory
Browse clinical research sites, groups, and studies.
Threatened Preterm Labour: Vaginal Progesterone Versus Nifedipine
Sponsor: Dr Mudassar Saeed Pansota
Summary
So, a number of studies have been conducted worldwide to find a suitable agent for arresting threatened preterm labor. The current study is planned to examine the effectiveness of nifedipine and progesterone in the treatment of threatened preterm labor (TPL). The result of this study will be used to recommend the best treatment modality in our population to reduce the risk of preterm labor
Official title: Efficacy of Vaginal Progesterone and Nifedipine in Inhibiting Threatened Preterm Labour
Key Details
Gender
FEMALE
Age Range
18 Years - 35 Years
Study Type
INTERVENTIONAL
Enrollment
160
Start Date
2025-11-30
Completion Date
2026-05-29
Last Updated
2026-06-16
Healthy Volunteers
No
Conditions
Interventions
Vaginal progesterone 200mg daily
In Group B, participants will be instructed to use vaginal micronized progesterone tablets at a dosage of 200mg once daily or until reaching 37 weeks of gestational age or until cervical dilation exceeded 4cm (for a duration of 48 hours)
Nifedipine 20 Mg
In Group A, participants will receive oral nifedipine at a dose of 20mg every 30 minutes for three doses initially, followed by long-acting nifedipine SR 20mg every 12 hours until reaching 37 weeks of gestational age or until cervical dilation exceeded 4cm (for a duration of 48 hours).
Locations (1)
Hilal-e-ahmar Hospital
Faisalabad, Punjab Province, Pakistan