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Stimulating the Aging Brain Using Brain and Sensory Stimulation
Sponsor: Medical College of Wisconsin
Summary
The goal of this project is to investigate whether transcranial electrical stimulation and sensory stimulation affect language outcomes in individuals with primary progressive aphasia (PPA). The main questions it aims to answer are: Does transcranial alternating current stimulation (tACS) affect verbal short-term memory (STM) in individuals with PPA? Does a single session of multisensory stimulation affect verbal STM in individuals with PPA? Researchers will compare active tACS to sham tACS (a fake stimulation condition) to see if active tACS improves verbal STM. Researchers will compare pre-multisensory stimulation to post-stimulation performance to see if multisensory stimulation improves verbal STM. Participants will: Undergo EEG, MRI (anatomical and functional) May complete a cognitive exam Undergo tACS over 3 separate sessions Undergo multisensory stimulation Complete language tasks before, during and/or after stimulation
Official title: Stimulating the Aging Brain: Noninvasive Brain and Sensory Stimulation Strategies in Aging
Key Details
Gender
All
Age Range
45 Years - Any
Study Type
INTERVENTIONAL
Enrollment
20
Start Date
2026-06-01
Completion Date
2035-05-30
Last Updated
2026-06-16
Healthy Volunteers
No
Conditions
Interventions
tACS or multisensory stimulation
Active or sham tACS Light and/or sound flickers
Locations (1)
Medical College of Wisconsin
Milwaukee, Wisconsin, United States