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NOT YET RECRUITING
NCT07650214
NA

Study on the Effects and Mechanisms of Probiotic Supplementation in Ameliorating Uric Acid Metabolism in Asymptomatic Hyperuricemic Individuals

Sponsor: Sun Yat-sen University

View on ClinicalTrials.gov

Summary

This study aims to utilize a randomized controlled trial in asymptomatic hyperuricemic individuals to clarify the effects of four probiotic strains including Lactobacillus acidophilus on serum uric acid levels, pathways of uric acid synthesis, degradation and excretion, hyperuricemia-induced oxidative stress and chronic inflammatory responses, uric acid-related metabolites, gut microbiota composition and diversity.

Key Details

Gender

All

Age Range

18 Years - 65 Years

Study Type

INTERVENTIONAL

Enrollment

68

Start Date

2026-07-01

Completion Date

2027-12-31

Last Updated

2026-06-16

Healthy Volunteers

No

Interventions

DIETARY_SUPPLEMENT

Probiotic

Probiotic products (6 × 10\^9 CFU per day)

DIETARY_SUPPLEMENT

Placebo

Placebo (without probiotics, with other ingredients consistent with probiotic products)

Locations (1)

Sun Yat-sen University

Shenzhen, Guangdong, China