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ACTIVE NOT RECRUITING
NCT07650409
NA

A Dietary Intervention (Soy Soft Pretzels) for Reducing Chronic Inflammation in Obese Individuals

Sponsor: Ohio State University Comprehensive Cancer Center

View on ClinicalTrials.gov

Summary

This clinical trial compares the effects of soy soft pretzels versus wheat pretzels on inflammatory markers in individuals with obesity. Obesity is a serious public health problem that can lead to chronic inflammation, which is associated with many negative health conditions and some types of cancer. Soy versus wheat pretzels may be processed by the body differently, and the components in these pretzel snacks may be helpful for reducing inflammation. Soy soft pretzels are made with soybeans, which contain many natural chemicals that may be beneficial to human health, such as isoflavones. Existing research has suggested that diets enriched with isoflavones may help reduce inflammation. However, the relationship between soy-rich diets and the immune systems of obese individuals is not well understood. This trial may help researchers determine whether soy soft pretzels are useful for lowering markers of chronic inflammation, compared to wheat pretzels, in individuals with obesity.

Official title: Examining the Efficacy of a Soft Soy Pretzel Intervention in Altering Chronic Inflammation and Immune Profiles in Obese Individuals

Key Details

Gender

MALE

Age Range

18 Years - 49 Years

Study Type

INTERVENTIONAL

Enrollment

30

Start Date

2025-06-01

Completion Date

2026-12-31

Last Updated

2026-06-16

Healthy Volunteers

Yes

Interventions

PROCEDURE

Biospecimen Collection

Undergo collection of blood and urine samples

OTHER

Dietary Intervention

Consume SSPs

OTHER

Dietary Intervention

Consume WPs

OTHER

Questionnaire Administration

Ancillary studies

Locations (1)

Ohio State University Comprehensive Cancer Center

Columbus, Ohio, United States