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A Dietary Intervention (Soy Soft Pretzels) for Reducing Chronic Inflammation in Obese Individuals
Sponsor: Ohio State University Comprehensive Cancer Center
Summary
This clinical trial compares the effects of soy soft pretzels versus wheat pretzels on inflammatory markers in individuals with obesity. Obesity is a serious public health problem that can lead to chronic inflammation, which is associated with many negative health conditions and some types of cancer. Soy versus wheat pretzels may be processed by the body differently, and the components in these pretzel snacks may be helpful for reducing inflammation. Soy soft pretzels are made with soybeans, which contain many natural chemicals that may be beneficial to human health, such as isoflavones. Existing research has suggested that diets enriched with isoflavones may help reduce inflammation. However, the relationship between soy-rich diets and the immune systems of obese individuals is not well understood. This trial may help researchers determine whether soy soft pretzels are useful for lowering markers of chronic inflammation, compared to wheat pretzels, in individuals with obesity.
Official title: Examining the Efficacy of a Soft Soy Pretzel Intervention in Altering Chronic Inflammation and Immune Profiles in Obese Individuals
Key Details
Gender
MALE
Age Range
18 Years - 49 Years
Study Type
INTERVENTIONAL
Enrollment
30
Start Date
2025-06-01
Completion Date
2026-12-31
Last Updated
2026-06-16
Healthy Volunteers
Yes
Interventions
Biospecimen Collection
Undergo collection of blood and urine samples
Dietary Intervention
Consume SSPs
Dietary Intervention
Consume WPs
Questionnaire Administration
Ancillary studies
Locations (1)
Ohio State University Comprehensive Cancer Center
Columbus, Ohio, United States