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NCT07650487

Perioperative Myocardial Injury in Patients Undergoing Coronary Artery Bypass Grafting: A Prospective Clinical Study

Sponsor: Second Hospital of Jilin University

View on ClinicalTrials.gov

Summary

Perioperative myocardial injury (PMI) following coronary artery bypass grafting (CABG) is associated with postoperative morbidity, mortality, and long-term outcomes. High-sensitivity troponin assays and cardiac MRI offer reliable diagnostic tools for PMI, but evidence regarding optimal diagnostic thresholds and perioperative imaging strategy is limited. This prospective clinical study aims to determine the incidence of perioperative myocardial injury using multimodal assessments including high-sensitivity troponin, electrocardiogram, echocardiography, cardiac MRI, and perioperative cardiovascular events.

Official title: Prospective Clinical Study for Evaluation of Perioperative Myocardial Injury Using High-Sensitivity Troponin and Cardiac MRI in Patients Undergoing Coronary Artery Bypass Grafting (CABG)

Key Details

Gender

All

Age Range

21 Years - 80 Years

Study Type

OBSERVATIONAL

Enrollment

150

Start Date

2026-07-01

Completion Date

2027-07-30

Last Updated

2026-06-16

Healthy Volunteers

No

Interventions

DIAGNOSTIC_TEST

High-Sensitivity Troponin

High-sensitivity troponin levels are measured preoperatively, predischarge, and at 6-month follow-up to assess perioperative myocardial injury.

DIAGNOSTIC_TEST

Cardiac MRI

A diagnostic assessment panel including high-sensitivity troponin testing, electrocardiography, echocardiography, and cardiac magnetic resonance imaging performed during the perioperative period.

Locations (1)

the Second Hospital of Jilin University

Changchun, Jilin, China