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RECRUITING
NCT07650682

Mathematical Modeling of Blood Sugar and Hormone Responses in Insulin-Dependent Type 2 Diabetes

Sponsor: Clinical Nutrition Research Center, Illinois Institute of Technology

View on ClinicalTrials.gov

Summary

This observational study aims to collect detailed metabolic and physiologic data from adults with insulin-dependent type 2 diabetes mellitus following consumption of a mixed meal tolerance test. Participants will undergo frequent blood sampling over a 4-hour period after consuming a standardized liquid mixed meal to measure glucose, insulin, glucagon, C-peptide, and triglyceride responses. Participants will also use continuous glucose monitoring and wearable physical activity tracking devices during free-living conditions. The purpose of this study is to develop mathematical models and digital representations ("digital twins") of people with type 2 diabetes mellitus. These models may help researchers better understand metabolic responses to meals, physical activity, and diabetes treatments, and may support future development of personalized diabetes technologies and therapies.

Official title: Mathematical Modeling of Type 2 Diabetes Mellitus

Key Details

Gender

All

Age Range

18 Years - 65 Years

Study Type

OBSERVATIONAL

Enrollment

25

Start Date

2026-05-20

Completion Date

2027-03-20

Last Updated

2026-06-16

Healthy Volunteers

No

Locations (1)

Illinois Institute of Technology

Chicago, Illinois, United States