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Treadmill Aerobic Training and Quality of Life in Anemic Females
Sponsor: Cairo University
Summary
This randomized controlled trial investigates the effects of an 8-week structured treadmill aerobic training program on physical fitness and health-related quality of life in young adult females diagnosed with mild-to-moderate iron deficiency anemia. Sixty participants are randomly allocated into two equal groups of thirty. Group A (Experimental) receives standard daily oral iron therapy combined with a supervised moderate-intensity treadmill exercise program 3 times per week (30-40 minutes at 60-70% maximum heart rate). Group B (Control) receives standard oral iron therapy with no structured exercise. The study primary outcome measures the Physical Fitness Index (PFI) using the modified submaximal 3-minute Harvard Step Test, alongside secondary quality of life outcomes (SF-12 questionnaire), to prove that active cardiovascular training reverses physical deconditioning where iron supplements alone fall short.
Official title: Aerobic Treadmill Training Improves Exercise Tolerance and Health-Related Quality of Life in Young Adult Females With Iron Deficiency Anemia: A Randomized Controlled Trial
Key Details
Gender
FEMALE
Age Range
18 Years - 28 Years
Study Type
INTERVENTIONAL
Enrollment
60
Start Date
2025-11-15
Completion Date
2026-01-15
Last Updated
2026-06-16
Healthy Volunteers
No
Interventions
Treadmill Aerobic Exercise
Supervised progressive treadmill walking program for 8 weeks, 3 times/week. Each session lasted 35-40 minutes including 5 minutes warm-up (at 2.0-3.0 km/h), 25-30 minutes active aerobic walking at 60-70% of age-predicted max HR, and 5 minutes cool-down.
Standard Medical Care and Nutritional Protocol
All participants in both groups received standard physician-prescribed medical care (including oral iron supplementation) and a standardized, culturally tailored, cost-effective nutritional protocol rich in heme and non-heme iron with absorption enhancers (e.g., Vitamin C) and restriction of iron inhibitors.
Locations (1)
Outpatient Clinics, Faculty of Physical Therapy, Horus University
New Damietta, Damietta Governorate, Egypt