Clinical Research Directory

Inclusion Criteria: 1. Age ≥ 60 years; 2. Diagnosis of ischemic stroke; (1)Ischemic stroke is defined as clinically manifest acute neurological deficits linked to an acute cerebral infarct in the anterior circulation; (2)Central retinal artery occlusion or likely central retinal artery occlusion are not considered ischemic strokes in the context of this trial; 3. Randomization within 72 hours of symptom onset; 4. Ability to provide written informed consent; 5. Baseline NIHSS \>=4; 6. Pre-stroke mRS \<=2; Exclusion Criteria: 1. Suspected lack of compliance; 2. Presence of moderate to severe dysphagia; 3. Current participation in other interventional trials or recent participation (within the last 30 days) in an interventional trial; 4. Known allergy or hypersensitivity to trial compounds components or placebo; 5. No known history before randomization of imminently life-shortening medical conditions or any other reason, including any physical, psychological, or psychiatric condition that in the investigator's opinion would compromise the safety or interfere with the subject's participation in this study, or would make the subject an unsuitable candidate to receive study drug, or would put the subject at risk by participating in the study; 6. Malignant diseases including active malignancies with a life expectancy of less than 3 months; 7. Major gastro-intestinal (GI) surgery, chronic inflammatory diseases of the gut and significant GI-neoplasms;